Project dates: September 2025 - August 2030
Principal Investigator: Cunningham B (contact PI)
Principal Investigator: Bashir R
Principal Investigator: Valera E
An important component of ending the HIV, HBV and HCV epidemics is the broad availability of rapid, inexpensive, multiplexed, and ultrasensitive viral load monitoring “triple test” in whole blood that provides the same accuracy as laboratory tests but delivers sample-to-answer results in point of care settings. This project will develop and validate an integrated set of innovative technologies that perform the sample preparation, assay protocol, and electronic biosensor readout within an inexpensively manufacturable microfluidic cartridge that interfaces with a simple, compact, and inexpensive detection instrument. The system performance will be characterized using artificially prepared test samples and validated with clinical specimens, while the design will be iteratively guided by a scientific advisory group to improve access to viral testing.
Abstract on NIH RePORTER