ResearchProjects

Strengthening Buprenorphine Treatment for Individuals in Carceral settings (STAND): A Hybrid Implementation-effectiveness Trial of Long-acting Injectable Versus Sublingual Buprenorphine
Funded by: National Institute on Drug Abuse
Project dates: September 2025 - May 2030
Principal Investigator: Lee, Joshua
Principal Investigator: Gryczynski J
Principal Investigator: Marsch L
Principal Investigator: Springer S
PROJECT DESCRIPTION

This study aims evaluate the effectiveness of long-acting injectable buprenorphine (XRB) and sublingual buprenorphine (SLB) among incarcerated adults preparing for reentry into the community across three correctional sites (Connecticut, New Hampshire and Delaware).

The findings will generate critical data on treatment retention, implementation feasibility, and relative costs, providing insights for correctional systems, healthcare providers, public health authorities, and policymakers. By focusing on a high-risk population, the study seeks to address gaps in care and improve continuity of treatment, with the potential to reduce post-release overdose risk, enhance long-term recovery outcomes, and mitigate the broader societal and economic impact of opioid addiction.

Abstract on NIH RePORTER