Project dates: September 2022 - September 2026
Principal Investigator: Renn TR
This study adapted an existing evidence-based trauma intervention for posttraumatic stress disorder (PTSD), Skills Training in Affective and Interpersonal Regulation with Narrative Therapy (STAIR-NT) for patients in a methadone maintenance treatment (MMT) program who were engaged in illicit opioid-stimulant polysubstance use.
After a rigorous adaption process informed by the ADAPT-ITT framework, a pilot randomized control trial examined implementation (i.e., feasibility, acceptability) and short-term polysubstance use and PTSD symptomology outcomes to inform a future multi-site trial. Addressing trauma among individuals engaged in MMT is a critical opportunity to provide effective treatment that is responsive to the needs of individuals who engage in polysubstance use, thereby reducing the severity of polysubstance use and attendant risks of overdose.
Abstract on NIH RePORTERAdaption of a posttraumatic stress disorder intervention for patients who use stimulants and opioids in the opioid treatment programme setting
European Journal of Psychotraumatology, 17 (1), 2687928. doi: 10.1080/20008066.2026.2687928. PMCID: PMC13347842.
Renn T, Griffin B, Kumaravelu V, Ventuneac A, Santacatterina M, Bunting AM (2024).
Study protocol for a randomized controlled trial to adapt a posttraumatic stress disorder intervention of patients with opioid-stimulant polysubstance use receiving methadone maintenance treatment
BMC Psychiatry, 24, 879. doi: 10.1186/s12888-024-06348-0. PMCID: PMC11616292.