Feasibility of point-of-care urine self-testing to measure tenofovir adherence and predict viral suppression
Abstract
This study is the first to demonstrate the feasibility of at-home adherence monitoring using a point-of-care urine assay for tenofovir (TFV). Undetectable TFV is strongly associated with lower viral suppression (odds ratio, 0.19, 95% CI, 0.10–0.34; P < .001), supporting a streamlined, effective approach for monitoring adherence between viral load assessments.
Full citation:
Buccheri R, Spinelli MA, Heise MJ, Glidden DV, Sassaman K, Martinson T, Schmidt HR, D'Angelo AB, Duncan DT, Horvath KJ, Hirshfield S, Williams RS, Johnson MO, Grov C, Carrico A, Gandhi M (2025). Feasibility of point-of-care urine self-testing to measure tenofovir adherence and predict viral suppression
Open Forum Infectious Diseases, 12 (6), ofaf300. doi: 10.1093/ofid/ofaf300. PMCID: PMC12131155.