ResearchProjects

Injecting drug use is driving many HIV epidemics in low and middle-income countries. This study will utilize large respondent driven sampling surveys to identify HIV+ persons who inject drugs in Haiphong, Viet Nam, followed by strong peer support to link them to HIV care and reach viral suppression. The goal is to reduce population viral load, reduce HIV incidence, and “end the HIV epidemic” among persons who inject drugs in Haiphong.

Abstract on NIH RePORTER

Quynh BTN, Le LTT, Nguyen HT, Nguyen TB, Rapoud D, Quillet C, Tran HT, Vallo R, Thanh NTT, Michel L, Weiss L, Van de Perre P, Vinh VH, Vinh VH, Oanh KTH, Des Jarlais D, Huong DT, Khue PM, Laureillard D, Moles JP (2023).
HCV RNA quantification by a domestic commercial assay: A case study among people who inject drugs in Vietnam
Diagnostics, 13 (22), 3456. doi: 10.3390/diagnostics13223456. PMCID: PMC10670863.

Feelemyer J, Des Jarlais DC, Nagot N, Huong DT, Oanh KTH, Khue PM, Giang HT, Thanh NTT, Cleland CM, Arasteh K, Caniglia E, Chen Y, Bart G, Moles JP, Vinh VH, Vallo R, Quillet C, Rapoud D, Le SM, Michel L, Laureillard D, Khan MR (2024).
Utility of self-report antiretroviral adherence for predicting HIV viral load among persons who inject drugs in Hai Phong Vietnam: Assessing differences by methamphetamine use
AIDS Care, 36 (4), 553-560. doi: 10.1080/09540121.2023.2275041. PMCID: PMC10932855.

Feelemyer J, Des Jarlais D, Nagot N, Huong DT, Oahn KTH, Khue PM, Giang HT, Thanh NTT, Cleland CM, Arasteh K, Caniglia E, Chen Y, Bart G, Moles JP, Vinh VH, Vallo R, Quillet C, Rapoud D, Le SM, Michel L, Laureillard D, Khan MR (2023).
Association between recent methamphetamine use, antiretroviral therapy and HIV viral load; a mediation analysis from a cohort of HIV positive persons who inject drugs in Hai Phong, Vietnam
International Journal of STD and AIDS, 34 (4), 236-244. doi: 10.1177/09564624221142366. PMCID: PMC10089109.

Giang HT, Nguyen DQ, Khue PM, Quillet C, Oanh KTH, Thanh NTT, Vallo R, Feelemyer J, Vinh VH, Rapoud D, Michel L, Laureillard D, Moles JP, Des Jarlais D, Nagot N, Huong DT (2023).
Gender differences in HIV, HCV risk and prevention needs among people who inject drug in Vietnam
AIDS and Behavior, 27 (6), 1989-1997. doi: 10.1007/s10461-022-03932-x. PMCID: PMC10149475.

Durand M, Nagot N, Quynh BTN, Vizeneux A,, Linh LTT, Huong TD, Binh NT, Rapoud D, Vallo R, Quillet C, Hong HT, Michel L, Thanh NTT, Oanh KTT, Vinh VH, Feelemyer J, Vande Perre P, Des Jarlais D, Khue PM, Laureillard D, Moles JP (2022).
Long-term persistence of mitochondrial DNA instability among HCV-cured people who inject drugs
Biomedicines, 10 (10), 2541. doi: 10.3390/biomedicines10102541. PMCID: PMC9599189.

Huong DT, Moles JP, Khue PM, Vallo R, Giang HT, Vinh VH, Oanh KTH, Thanh NTT, Nguyen DQ, Quillet C, Rapoud D, Van de Perre P, Castellani J, Feelemyer J, Michel L, Laureillard D, Des Jarlais D, Nagot N (2022).
A community-based intervention to decrease the prevalence of HIV viremia among people who inject drugs in Vietnam
Lancet Regional Health - Western Pacific, 27, 100538. doi: 10.1016/j.lanwpc.2022.100538. PMCID: PMC9287471.

Durand M, Nagot N, Michel L, Le SM, Huong DT, Vallo R, Vizeneux A, Rapoud D, Giang HT, Quillet C, Thanh NTT, Oanh KTH, Vinh VH, Feelemyer J, Vande Perre P, Minh KP, Laureillard D, Des Jarlais D, Moles JP (2022).
Mental disorders are associated with leukocytes telomere shortening among people who inject drugs
Frontiers in Psychiatry, 13, 846844. doi: 10.3389/fpsyt.2022.846844. PMCID: PMC9247253.

Nagot N, Vinh VH, Thuy TTD, Oanh KTH, Rapoud D, Giang HT, Quillet C, Khue PM, Vallo R, Thanh NTT, Castellani J, Feelemyer J, Des Jarlais DC, Nguyen LP, Van Le HV, Nguyen NV, Vo LNQ, Huong DT, Moles JP, Laureillard D (2022).
Alarming tuberculosis rate among people who inject drugs in Vietnam
Open Forum Infectious Diseases, 9 (2), ofab548. doi: 10.1093/ofid/ofab548. PMCID: PMC8801226.

Le SM, Trouiller P, Huong DT, Oanh KTH, Khue PM, Vallo R, Rapoud D, Quillet C, Nguyen TL, Nguyen DQ, Tranh NTT, Giang HT, Feelemyer J, Vinh VH, Moles JP, Doan HQ, Laureillard D, Des Jarlais DC, Nagot N, Michel L, DRIVE Study Team (2022).
Development and assessment of a community-based screening tool for mental health disorders among people who inject drugs
Drug and Alcohol Review, 41 (3), 697-705. doi: 10.1111/dar.13402. PMCID: PMC10150937.

Des Jarlais DC, Arasteh K, Huong DT, Oanh KTH, Feelemyer JP, Khue PM, Giang HT, Thanh NTT, Vinh VH, Le SM, Vallo R, Quillet C, Rapoud D, Michel L, Laureillard D, Moles JP, Nagot N, DRIVE Study Team (2021).
Using large-scale respondent driven sampling to monitor the end of an HIV epidemic among persons who inject drugs in Hai Phong, Viet Nam
PLoS One, 16 (11), e0259983. doi: 10.1371/journal.pone.0259983. PMCID: PMC8601441.

Durand M, Nagot N, Quynh BTN, Vallo R, Linh LTT, Huong DT, Binh NT, Rapoud D, Quillet C, Hong TT, Michel L, Tranh NTT, Oanh KTT, Vinh VH, Feelemyer J, Perre PV, Des Jarlais D, Khue PM, Laureillard D, Moles JP (2021).
Mitochondrial genotoxicity of hepatitis C treatment among people who inject drugs
Journal of Clinical Medicine, 10 (21), 4824. doi: 10.3390/jcm10214824. PMCID: PMC8584601.

Vinh VH, Vallo R, Giang HT, Huong DT, Oanh KTH, Khue PM, Thanh NTT, Quillet C, Rapoud D, Michel L, de Perre PV, Feelemyer J, Moles JP, Cournil A, Des Jarlais D, Laureillard D, Nagot N (2021).
A cohort study revealed high mortality among people who inject drugs in Hai Phong, Vietnam
Journal of Clinical Epidemiology, 139, 38-48. doi: 10.1016/j.jclinepi.2021.07.007. PMCID: PMC10116693.

Des Jarlais DC, Feelemyer J, Arasteh K, Huong DT, Oanh KTH, Khue PM, Giang HT, Thanh NTT, Moles JP, Vinh VH, Vallo R, Quillet C, Rapoud D, Michel L, Laureillard D, Nagot N (2021).
The methamphetamine epidemic among persons who inject heroin in Hai Phong, Vietnam
Journal of Substance Abuse Treatment, 126, 108320. doi: 10.1016/j.jsat.2021.108320. PMCID: PMC8197775.

Rapoud D, Quillet C, Khue PM, Vinh VH, Binh NT, Thanh NTT, Hong TT, Moles JP, Vallo R, Michel L, Feelemyer J, Weiss L, Lemoine M, Vickerman P, Fraser H, Huong DT, Oanh KTH, Des Jarlais D, Nagot N, Laureillard D (2020).
Towards HCV elimination among people who inject drugs in Hai Phong, Vietnam: Study protocol for an effectiveness-implementation trial evaluating an integrated model of HCV care (DRIVE-C: DRug use & Infections in ViEtnam-hepatitis C)
BMJ Open, 10 (11), e039234. doi: 10.1136/bmjopen-2020-039234. PMCID: PMC7677340.

Des Jarlais DC, Huong DT, Oanh KTH, Feelemyer JP, Arasteh K, Khue PM, Giang HT, Thanh NTT, Vinh VH, Le SM, Vallo R, Quillet C, Rapoud D, Michel L, Laureillard D, Moles JP, Nagot N (2020).
Ending an HIV epidemic among persons who inject drugs in a middle-income country: Extremely low HIV incidence among persons who inject drugs in Hai Phong, Viet Nam
AIDS, 34 (15), 2305-2311. doi: 10.1097/QAD.0000000000002712. PMCID: PMC8608372.

Le SM, Trouiller P, Huong DT, Oanh KTH, Khue PM, Vallo R, Rapoud D, Quillet C, Nguyen TL, Nguyen DQ, Thanh NTT, Giang HT, Feelemyer J, Vinh VH, Moles JP, Doan HQ, Laureillard D, Des Jarlais DC, Nagot N, Michel L (2020).
Daily heroin injection and psychiatric disorders: A cross-sectional survey among people who inject drugs (PWID) in Haiphong, Vietnam
Drug and Alcohol Dependence, 216, 108334. doi: 10.1016/j.drugalcdep.2020.108334. PMCID: PMC10290903.

Riondel A, Huong DT, Michel L, Peries M, Oanh KTH, Khue PM, Thanh NTT, Giang HT, Vallo R, Cournil A, Rapoud D, Quillet C, Laureillard D, Vinh VH, Moles JP, Feelemyer J, Hammett T, Des Jarlais D, Nagot N (2020).
Towards targeted interventions in low- and middle-income countries: Risk profiles of people who inject drugs in Haiphong (Vietnam)
BioMed Research International, 2020, 8037193. doi: 10.1155/2020/8037193. PMCID: PMC7502134.

Moles JP, Vallo R, Khue PM, Huong DT, Oanh KTH, Nguyen TT, Giang HT, Thanh NTT, Vinh VH, Thi TAB, Peries M, Arasteh K, Quillet C, Feelemyer J, Michel L, Des Jarlais D, Laureillard D, Nagot N (2020).
HIV control programs reduce HIV incidence but not HCV incidence among people who inject drugs in HaiPhong, Vietnam
Scientific Reports, 10 (1), 6999. doi: 10.1038/s41598-020-63990-w. PMCID: PMC7181676.

Nguyen TT, Luong AN, Thanh NTT, Chauvin C, Feelemyer J, Nagot N, Des Jarlais D, Giang LM, Jauffret-Roustide M (2019).
Struggling to achieve a ‘normal life’: A qualitative study of Vietnamese methadone patients
International Journal of Drug Policy, 68, 18-26. doi: 10.1016/j.drugpo.2019.03.026. PMCID: PMC6535358.

Khue PM, Vallo R, Huong DT, Oanh KTH, Des Jarlais DC, Peries M, Le SM, Rapoud D, Quillet C, Thanh NTT, Giang HT, Feelemyer J, Vinh VH, Moles JP, Pham TX, Laureillard D, Nagot N, Michel L, DRIVE Study Team (2018).
Psychiatric comorbidities among people who inject drugs in Hai Phong, Vietnam: The need for screening and innovative interventions
BioMed Research International, 2018, 8346195. doi: 10.1155/2018/8346195. PMCID: PMC6193349.

Feelemyer J, Huong DT, Khue PM, Giang HT, Thanh NTT, Oanh KTH, Arasteh K, Moles JP, Vinh VH, Vallo R, Quillet C, Rapoud D, Michel L, Hammett T, Laureillard D, Nagot N, Des Jarlais D, Drive Study Team (2018).
Increased methamphetamine use among persons who inject drugs in Hai Phong, Vietnam, and the association with injection and sexual risk behaviors
Journal of Psychoactive Drugs, 50 (5), 382-389. doi: 10.1080/02791072.2018.1508790. PMCID: PMC6379246.

Hammett TM, Nguyen TT, Oanh KTH, Nguyen TH, Giang LM, Huong DT, Nagot N, Des Jarlais DC (2018).
The relationship between health policy and public health interventions: A case study of the DRIVE project to “end” the HIV epidemic among people who inject drugs in Haiphong, Vietnam
Journal of Public Health Policy, 39 (2), 217-230. doi: 10.1057/s41271-017-0115-7. PMCID: PMC5970070.

Des Jarlais D, Khue PM, Feelemyer J, Arasteh K, Huong DT, Oanh KTH, Giang HT, Thanh NTT, Vinh VH, Heckathorn DD, Moles JP, Vallo R, Quillet C, Rapoud D, Michel L, Laureillard D, Hammett T, Nagot N (2018).
Using dual capture/recapture studies to estimate the population size of persons who inject drugs (PWID) in the city of Hai Phong, Vietnam
Drug and Alcohol Dependence, 185, 106-111. doi: 10.1016/j.drugalcdep.2017.11.033. PMCID: PMC5889732.